It all started when Rock, who was hosting the event, aimed a joke at Jada’s shaved head, comparing her to Demi Moore in the 1997 film G.I. Jane.
The Bad Moms actress had previously spoken about living with alopecia, a disease that attacks hair follicles and causes hair loss.
After Rock said: “Jada, can’t wait for G.I. Jane 2,” Smith walked up on stage and to everyone’s astonishment, smacked him.
When he returned to his seat, Smith yelled: “Keep my wife’s name out of your f***ing mouth.”
Awkwardly, the night ended with Smith winning the Best Actor award for his role in King Richard – however, the infamous slap overshadowed what should’ve been the crowning moment in his career.